Taken anally

View Full Version : Headache relief taken anally. Send questions for Cecil Adams to: cecil straightdope. Your direct line to thousands of the smartest, hippest people on the planet, plus a few total dipsticks. As I was swallowing some acetaminophen, I got to wondering, would this pill work equally well, if taken anally? Y'know, to really put the "anal" in "analgesic".
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Rectal administration

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Absorption kinetics of rectally and orally administered ibuprofen.

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Absorption kinetics of rectally and orally administered ibuprofen.

This leaflet gives tips about how to give rectal medicines suppositories and enemas to children. This leaflet has been written specifically about the use of medicines in children. Please read this leaflet carefully.
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Drugs administered PR have a faster action than via the oral route and a higher bio-availability — that is, the amount of effective drug that is available is greater as it has not been influenced by upper gastrointestinal tract digestive processes. Rectal absorption results in more of the drug reaching the systemic circulation with less alteration on route. As well as being a more effective route for delivering medication, rectal administration also reduces side-effects of some drugs, such as gastric irritation, nausea and vomiting Lowry, , para 2. Rectal medications are given for their local effects in the gastrointestinal system e.
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